This is a phase I, an open label, single dose, and parallel group study to assess short term pharmacodynamics and safety of GSK933776. The effect on the beta amyloid levels will be assessed in early (MCI) and mild Alzheimer's disease (AD) patients after a single dose of GSK933776 by i.v. administration.
For more information on this study, visit the Study Record Detail of the respective clinical trial here.
Manuscripts citing this dataset
- Modulation of β-amyloid by a single dose of GSK933776 in patients with mild Alzheimer's disease: a phase I study. 2014. DOI: https://doi.org/10.1186/alzrt249
- First administration of the Fc-attenuated anti-β amyloid antibody GSK933776 to patients with mild Alzheimer's disease: a randomized, placebo-controlled study. 2015. DOI: https://doi.org/10.1371/journal.pone.0098153
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